Cytokines: Shared receptors, distinct functions

نویسنده

  • James P DiSanto
چکیده

That the signal transduction pathways used by the cytokines IL-2 and IL-15 are identical would suggest that these cytokines have redundant roles in lymphoid development; instead, IL-2 is the guardian of thymus-derived T-cell homeostasis, while interleukin-15 promotes extrathymic development of T and NK cells.

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عنوان ژورنال:
  • Current Biology

دوره 7  شماره 

صفحات  -

تاریخ انتشار 1997